Dr. Abigail Koppes-
Principal Investigator

Brent Buchinger

Parkinson’s disease is the second most common neurodegenerative disease, characterized by progressive losses in motor control and cognitive functioning. While recent work has hinted at a gut origin, research elucidating the mechanisms for this pathological pathway is lacking. Brent’s work aims to develop a novel microphysiological system mimicking the gut-brain axis with the goal of improving platforms for studying and understanding Parkinson’s disease.

Brent joined ABNEL in the summer of 2022 as a Chemical Engineering PhD student. Prior to his graduate studies at Northeastern University, Brent worked as an analytical chemist at Eurofins Food Integrity & Innovation. He obtained his BS in Chemical Engineering at the University of Wisconsin–Madison in December of 2019. At his undergraduate institution, Brent’s research focused on catalysis. However, his passions switched to biomedical engineering after researching chondrogenic differentiation during a summer internship at Case Western Reserve University in 2018.

B.S. Chemical Engineering
University of Wisconsin–Madison ’19
Madison, WI

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Bryan Schellberg – Quickest turn around review publication

Congratulations to our PhD student, Bryan Schellberg, on his recent review publication in the Journal of Biomedical Materials Research! Bryan's publication not only marks the lab's first in 2025 but also set a new record for fastest turn around review publication in...

What a tiny, 3D gut can tell us about gastrointestinal disorders

Principal investigators of ABNEL and LNNR, Dr. Abigail Koppes and Dr. Ryan Koppes, recently made headlines on Northeastern Global News. This recognition arises from their collaborative efforts on the development of microphysiological systems aimed at investigating the...