Publications
2022
Adam J. Bindas, Kyla N. Nichols, Nicole J. Roth, Ryan Brady, Abigail N. Koppes, Ryan A. Koppes. Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro. http://doi.org/10.1038/s41598-022-26543-x
Katelyn Neuman, Xiaoyu Zhang, Caroline Mills, Ryan Koppes, Laura H Lewis, Abigail Koppes. En route to next-generation nerve repair: static passive magnetostimulation modulates neurite outgrowth. http://doi.org/10.1088/1741-2552/acb103
Caroline Ghio, Joleen M. Soukup, Lisa A. Dailey, Andrew J. Ghio, Dina M. Schreinemachers, Ryan A. Koppes, Abigail N, Koppes. Lactate Production can Function to Increase Human Epithelial Cell Iron Concentration. http://doi.org/10.1007/s12195-022-00741-z
Kirstie Belanger, Abigail N. Koppes, Ryan A. Koppes. Impact of Non-Muscle Cells on Excitation-Contraction Coupling in the Heart and the Importance of In Vitro Models. http://doi.org/10.1002/adbi.202200117
Neuman K.E., Kenny A., Shi L., Koppes A.N., Koppes R.A.. Complex Material Properties of Gel-Amin: A Transparent and Ionically Conductive Hydrogel for Neural Tissue Engineering. http://doi.org/10.1159/000524692
Kyla N. Nichols, Abigail N. Koppes, Ryan A. Koppes. These organoids have some nerve: Uniting three germ layers in a human gastric model system. https://doi.org/10.1016/j.stem.2021.12.005
2021
Jonathan R Soucy, Gabriel Burchett, Ryan Brady, Kyla Nichols, David T Breault, Abigail N Koppes, Ryan A Koppes. Innervated adrenomedullary microphysiological system to model nicotine and opioid exposure. https://doi.org/10.1016/j.ooc.2021.100009
Adam J. Bindas, Subhash Kulkarni, Ryan A. Koppes, Abigail N. Koppes. Parkinson’s disease and the gut: Models of an emerging relationship. https://doi.org/10.1016/j.actbio.2021.03.071
Max A. Winkelman, Abigail N. Koppes, Ryan A. Koppes, and Guohao Dai. Bioenginneering the neurovascular niche to study the interaction of neural stem cells and endothelial cells. https://doi.org/10.1063/5.0027211
Kelly R. Stevens, Kristyn S.Masters, P. I. Imoukhuede, Karmella A.Haynes, Lori A. Setton, Elizabeth Cosgriff-Hernandez, Muyinatu A. Lediju Bell, Padmini Rangamani, Shelly E. Sakiyama-Elbert, Stacey D. Finley, Rebecca K.Willits, Abigail N. Koppes, Naomi C. Chesler, Karen L. Christman, Josephine B. Allen, Joyce Y. Wong, Hana El-Samad, Tejal A. Desai, Omolola Eniola-Adefeso. Fund Black scientists. https://doi.org/10.1016/j.cell.2021.01.011
2020
David Diaz Vera, Jonathan R. Soucy, Audrey Lee, Ryan A. Koppes, Abigail N. Koppes. Light irradiation of peripheral nerve cells: Wavelength impacts primary sensory neuron outgrowth in vitro. https://doi.org/10.1016/j.jphotobiol.2020.112105
Bindas, Adam J., Kulkarni, Subhash, Koppes, Ryan A., Koppes, Abigail N., Parkinson’s Disease and the Gut: Models of an Emerging Relationship. SSRN Preprint. http://dx.doi.org/10.2139/ssrn.3739626
Jonathan R Soucy, Gabriel Burchett, Ryan Brady, David T Breault, Abigail N Koppes, Ryan A Koppes. Innervated adrenomedullary microphysiological system to model prenatal nicotine and opioid exposure. Biorxiv Preprint. https://doi.org/10.1101/2020.09.22.308973
Daniel M. Ventre, Avery Cluff, Christian Gagnon, David Diaz Vera, Ryan A. Koppes, Abigail N. Koppes. The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro. August 2020. https://doi.org/10.1002/jnr.24700
Jon Soucy, Adam Bindas, Ryan Brady, Tess Torregrosa, Cailey Denocourt, Sanjin Hosic, Guohao Dai, Abigail Koppes, Ryan Koppes. Reconfigurable microphysiological systems for modeling innervation and multi-tissue interactions. July 2020. https://doi.org/10.1002/adbi.202000133
Sanjin Hosic, Will Lake, Eric Stas, Ryan Koppes, David T. Breault, Shashi K. Murthy, Abigail N. Koppes. Cholinergic Activation of Primary Human Derived Intestinal Epithelium Does Not Ameliorate TNF-α Induced Injury. June 2020. https://doi.org/10.1007/s12195-020-00633-0
Sanjin Hosic, Adam Bindas, Marissa L. Puzan, Will Lake, Jonathan Soucy, Fanny Zhou, Ryan A. Koppes, David T. Breault, Shashi K. Murthy, Abigail N. Koppes. Rapid prototyping of multilayer microphysiological systems. May 2020. https://doi.org/10.1021/acsbiomaterials.0c00190
Kyla Nichols, Ryan Koppes, Abigail Koppes. Recent advancements in microphysiological systems for neural development and disease. May 2020. https://doi.org/10.1016/j.cobme.2020.05.003
Tess Torregrosa, Sophie Webster, Chiamaka Aghaizu, Jonathan Soucy, Christopher Bertucci, Leigh Plant, Abigail Koppes, Ryan Koppes. Cryopreservation and functional analysis of cardiac autonomic neurons. July 2020. https://doi.org/10.1016/j.jneumeth.2020.108724
Jessica Snyder, CM Wang, AQ Zhang, Y Li, Josh Luchan, Sanjin Hosic, Ryan Koppes, Rebecca Lyn Carrier, Abigail Koppes. Materials and Microenvironments for Engineering the Intestinal Epithelium. Feb 2020. https://doi.org/10.1007/s10439-020-02470-8
2019
Jonathan R Soucy, Jody Askaryan, David Diaz, Abigail N Koppes, Nasim Annabi, and Ryan A Koppes. Glial cells influence cardiac permittivity as evidenced through in vitro and in silico models. Dec 2019. doi: 10.1088/1758-5090/ab4c0a
Jonathan R. Soucy, Adam J. Bindas, Abigail N. Koppes, and Ryan A. Koppes. Instrumented Microphysiological Systems for Real-time Measurement and Manipulation of Cellular Electrochemical Processes. Oct 2019. https://doi.org/10.1016/j.isci.2019.10.052
Christopher Bertucci, Ryan Koppes, Courtney Dumont, and Abigail Koppes. Neural responses to electrical stimulation in 2D and 3D in vitro environments. July 2019. https://doi.org/10.1016/j.brainresbull.2019.07.016
Alexis M. Ziemba, Anthony R. D’Amato, Taylor M. MacEwen, Devan L. Puhl, Abigail N. Koppes, Ryan A. Koppes, Michelle R. Lennartz, and Ryan J. Gilbert. Stabilized Interleukin-4-Loaded Poly(lactic-co-glycolic) Acid Films Shift Proinflammatory Macrophages toward a Regenerative Phenotype in Vitro. Feb 2019. https://doi.org/10.1021/acsabm.8b00769
2018
Jonathan R. Soucy, Ehsan Shirzaei Sani, Roberto Portillo Lara, David Diaz, Felipe Dias, Anthony S. Weiss, Abigail N. Koppes, Ryan A. Koppes, and Nasim Annabi. Photocrosslinkable Gelatin/Tropoelastin Hydrogel Adhesives for Peripheral Nerve Repair. Sept 2018. https://doi.org/10.1089/ten.tea.2017.0502
Hosic, Sanjin; Puzan, Marissa; Lake, Will; Zhao, Fanny; Koppes, Ryan; Breault, David; Koppes, Abigail. Rapid prototyping of a multilayer microphysiological system for primary human intestinal epithelial culture. bioRxiv 400721; doi: https://doi.org/10.1101/400721. PrePrint (Now Published).
Soucy, Jonathan; Askaryan, Jody; Diaz, David; Koppes, Abigail; Annabi, Nasim; Koppes, Ryan. Glial cells in the heart? Replicating the diversity of the myocardium with low-cost 3D models. bioRxiv 306233; doi: https://doi.org/10.1101/306233. PrePrint (Now Published).
Ventre, Daniel; Puzan, Marissa; Ashbolt, Emily*; Koppes, Abigail. Enhanced total neurite outgrowth and secondary branching in dorsal root ganglion neurons elicited by low intensity pulsed ultrasound. Journal of Neural Engineering. April 2018. DOI: 10.1088/1741-2552/aabeba
Puzan, Marissa; Legesse, Belete; Koppes, Ryan; Fenniri, Hicham; Koppes, Abigail. Bioactive Organic Rosette Nanotubes Support Sensory Neurite Outgrowth. ACS Biomaterials Science & Engineering. March 2018. DOI: 10.1021/acsbiomaterials.8b00326
Puzan, Marissa; Hosic, Sanjin; Ghio, Caroline*; Koppes, Abigail. Enteric Nervous System Regulation of Intestinal Stem Cell Differentiation, Epithelial Monolayer Health, and Inflammation. Scientific Reports. April 2018. DOI:10.1038/s41598-018-24768-3
Soucy, Jonathan; Shirzaei Sani, Ehsan; Portillo Lara, Roberto; Diaz, David; Weis, Anthony; Koppes, Abigail; Koppes, Ryan; Annabi; Nasim. Photocrosslinkable Gelatin/Tropoelastin Hydrogels for Peripheral Nerve Repair. Tissue Engineering A. March 2018. DOI: 10.1089/ten.TEA.2017.0502
2017
Spencer, Andrew; Primbetova, Asel; Koppes, Abigail; Koppes, Ryan; Fenniri, Hicham; Annabi, Nasim. Electroconductive Gelatin Methacryloyl-PEDOT:PSS Composite Hydrogels: Design, Synthesis, and Properties. ACS Biomaterials Science & Engineering. March 2018. DOI: 10.1021/acsbiomaterials.8b00135
Biology and Engineering of Stem Cell Niches. Chapter 37 – Engineering the Niche for Intestinal Regeneration. Victor Hernandez-Gordillo, Abigail N. Koppes, Linda G. Griffith, David T. Breault, Rebecca L. Carrier. Edited by:Ajaykumar Vishwakarma and Jeffrey Karp. doi.org/10.1016/B978-0-12-802734-9.00037-8; ISBN: 978-0-12-802734-9
2016
DM Ventre, AN Koppes. The body acoustic: ultrasonic neuromodulation for translational medicine. Cells, Tissues, Organs. 2015/2016;202:23-41.
Abigail Koppes, Megha Kamath, Courtney Pfluger, Daniel Burkey, Mehmet R Dokmeci, Ling Wang, Rebecca Lyn Carrier. Complex, multi-scale small intestinal topography replicated in cellular growth substrates fabricated via chemical vapor deposition of Parylene C. Biofabrication 8(3): 2016. doi:10.1088/1758-5090/8/3/035011
AN Koppes, KW Keating, AL McGregor, RA Koppes, KR Kearns, AM Ziemba, CA McKay, JM Zuidema, CJ Rivet, RJ Gilbert, DM Thompson. (2016). Robust neurite extension following exogenous electrical stimulation within single walled carbon nanotube-composite hydrogels. Acta biomaterialia 39, 34-43. doi:10.1016/j.actbio.2016.05.014
2015
S Hosic, SK Murthy, AN Koppes (2015) Microfluidic Sample Preparation for Single Cell Analysis. Analytical chemistry 88 (1), 354-380
AN Koppes, DM Thompson. (2015). Neural innervation of engineered musculoskeletal tissues. Regenerative Engineering of Musculoskeletal Tissues and Interfaces, 293
2014
DM Thompson, AN Koppes, JG Hardy, CE Schmidt (2014). Electrical stimuli in the central nervous system microenvironment. Annual review of biomedical engineering 16, 397-430
AN Koppes, NW Zaccor, CJ Rivet, LA Williams, JM Piselli, RJ Gilbert, DM Thompson. (2014). Neurite outgrowth on electrospun PLLA fibers is enhanced by exogenous electrical stimulation. Journal of Neural Engineering, 11. doi:10.1088/1741-2560/11/
2009-2013
AN Koppes, AL Nordberg, GM Paolillo, NM Goodsell, HA Darwish, L Zhang. DM Thompson. (2013). Electrical stimulation of Schwann cells promotes sustained increases in neurite outgrowth. Tissue Engineering Part A, 20 (3-4), 494-506.
AN Koppes, AM Seggio, DM Thompson. (2011). Neurite outgrowth is significantly increased by the simultaneous presentation of Schwann cells and moderate exogenous electric fields. Journal of neural engineering, 8 (4).
BL Behan, DG DeWitt, DR Bogdanowicz, AN Koppes, SS Bale, et al. Single‐walled carbon nanotubes alter Schwann cell behavior differentially within 2D and 3D environments. Journal of Biomedical Materials Research Part A. 96 (1), 46-57
WH Fissell, A Dubnisheva, AN Eldridge, AJ Fleischman, AL Zydney, et al. High-performance silicon nanopore hemofiltration membranes. Journal of membrane science. 326 (1), 58-63
WH Fissell, S Manley, A Dubnisheva, J Glass, J Magistrelli, AN Eldridge, et al. Ficoll is not a rigid sphere. American Journal of Physiology-Renal Physiology. 293 (4), F1209-F1213
Katelyn Neuman’s Article Accepted for Publication
Katelyn Neuman, current graduate student of Dr. Ryan Koppes, had her article titled "En route to next-generation nerve repair: static passive magnetostimulation modulates neurite outgrowth" accepted for publication in the Journal of Neural Engineering. Her article...
Dr. Adam Bindas’ Paper is Published
Previous graduate student, Dr. Adam Bindas, successfully published his article "Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro" in Scientific Reports. Co-authored by current graduate student, Kyla Nichols, the article investigates...