Dr. Abigail Koppes-
Principal Investigator

Sources of Funding

Sjögren’s Foundation Pilot Research Award (Role: PI: Abigail Koppes)
Parsing dysautonomia in a dish: neural exposure to exogenous Sjögren’s patient derived serum


NIH NINDS R21 (Role: PI: Guohao Dai; Co-I: Ryan Koppes)
Bioengineer a humanized Autonomic Neurovascular Innervation on a Chip


NASA AMES NASA CASIS (Role: PI: Guohao Dai; Co-I: Abigail Koppes, Ryan Koppes, Jenny Zou, Roland Friedel)
Bioengineer long-lasting 3D neurovascular microphysiological system to model chronic inflammation mediated neurodegeneration


NIH NIA R21 (Role: PIs: Subhash Kulkarni/Abigail Koppes)
Developing a microphysiological system of a humanized Gut-Brain-Axis for age-associated transmissible neuropathologies


NIH NIBIB Trailblazer R21 (Role: PI: Benjamin Woolston)
Engineered Probiotics for Closed-Loop Control of Disease-Associated Gut Metabolites in Gut-On-Chip Models


$500K NSF CAREER CBET Award: 2045906 (Role: PI: Abigail Koppes)
Defining the regulators of enteric plasticity in engineered microfluidic environments


NIH Trailblazer: 1R21EB025395 (Role: PIs: Abigail Koppes/Ryan Koppes)
ENGINEERING A HUMANIZED GUT-ENTERIC-AXIS


R01 BRP: 5R01EB021908 (Role: CO-I, PIs: Rebecca Carrier/Linda Griffith)
GUMI: NEW IN VITRO PLATFORMS TO PARSE THE HUMAN GUT EPITHELIAL-MICROBIOME-IMMUNE AXIS 19IPLOI34760604


AHA Innovative Project Award: 19IPLOI34760604 (Role: CO-I, mPIs: Ryan Koppes/Guohao Dai)
BIOENGINEER AN AUTONOMIC NEUROVASCULAR SYSTEM TO EXPLORE INNERVATION OF ARTERIAL GRAFTS

Bryan Schellberg – Quickest turn around review publication

Congratulations to our PhD student, Bryan Schellberg, on his recent review publication in the Journal of Biomedical Materials Research! Bryan's publication not only marks the lab's first in 2025 but also set a new record for fastest turn around review publication in...

What a tiny, 3D gut can tell us about gastrointestinal disorders

Principal investigators of ABNEL and LNNR, Dr. Abigail Koppes and Dr. Ryan Koppes, recently made headlines on Northeastern Global News. This recognition arises from their collaborative efforts on the development of microphysiological systems aimed at investigating the...